Member 1 Subfamily B ATP Binding Cassette Transporter

A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

Also Known As:

ATP Binding Cassette Transporter, Subfamily B, Member 1; ABCB1 Protein; ATP Binding Cassette Transporter, Sub-Family B, Member 1; ATP-Binding Cassette, Sub-Family B, Member 1; CD243 Antigen; PGY-1 Protein; 1, P-Glycoprotein; ABCB1, ATP-Dependent Translocase; ATP Dependent Translocase ABCB1; Antigen, CD243; P Glycoprotein; P Glycoprotein 1; PGY 1 Protein; Protein, MDR1B; Translocase ABCB1, ATP-Dependent; ATP-Dependent Translocase ABCB1; MDR1 Protein; MDR1B Protein; Multidrug Resistance Protein 1; P-Glycoprotein; P-Glycoprotein 1

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
  - Carrier Proteins: 13306
    - Membrane Transport Proteins: 606
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
      - Ion Pumps: 63
        Anion Transport Proteins: 2
        Organic Anion Transporters: 381
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
    - Membrane Transport Proteins: 606
      - ATP-Binding Cassette Transporters: 2910
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028
      - Ion Pumps: 63
        Anion Transport Proteins: 2
        Organic Anion Transporters: 381
        ATP-Dependent Organic Anion Transporters
        Subfamily B ATP Binding Cassette Transporter: 262
        Member 1 Subfamily B ATP Binding Cassette Transporter: 7028

H Chai Selected Research

H Chai Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure